Skip to main content

Welcome to Clinical Research

Call Today to Qualify

Open Hours

Monday – Friday 8 am to 5pm

Gout

What is Gout?

- Gout is a subset of arthritis that is caused by the needle-like crystals of uric acid in your joints, muscle, and/or skin. The crystals form because your body is either overproducing or underexcreting uric acid, which can then group together to form structures that can cause large amounts of pain. Gout typically manifests in 'episodes', which can last from several days to a week. However, there may be as much as several years in between outbreaks in affected persons. 

Why Should You Care?
Causes
Risk Factors
Symptoms
Treatments
Resources

Why Should You Care?

- A little less than 1 out of 100 people in the U.S. have or will have gout at some point. 

                                                                                                                         Top

Causes

- Overproduction of uric acid  - Underexcretion of uric acid
- Certain medications  

                                                                                                                         Top

Risk Factors

- Obesity  - Family history   
- Age  - Being male
- Thyroid malfunctions  - Drinking large amounts of beer
- Exposure to lead  - Organ transplants

- Certain medications(1)

 
   - Diuretics  - Aspirin
   - Cyclosporine  - Levodopa
   - Purine - rich diet  
   - Dairy products appear to be good        - Vegetables with purine are fine
   - Organ meats increase risk  
      - Liver meat  - Calf tongue
      - etc.   

                                                                                                                         Top

Symptoms

-There are several stages of gout, which are marked by different symptoms.

 - Asymptomatic tissue deposition  
     - Typically no overt symptoms of arthritis, but hyperuracemia is present  

        - Gout crystals may have formed, but aren't causing flares

 
  - Acute flairs:  
     - Can last from days to weeks    
   - Present with:                           
      - Pain - Redness                                                  
      - Swelling  
   - Usually in joint of big toe  
      - Can be many joints in elderly


 

Intercritical Segments:  
    - After acute flairs, gout can be inactive until the next  
       - Without treatment, there will be another flare  
    - Interval between flairs will decrease over time  
    - Hyperuracemia continues
 
 

 - Chronic gout:

    - Form of chronic arthritis   
       - Sore / aching joints  
     - Tophi may form in cooler parts of the body  
        - Elbows                                                 - Outer ear                              
        - Fingerjoints   - Toes
        - Knees  

                                                                                                                         Top

Treatments

- Hyperuricemic medication  
- Physical therapy  
- Occupational therapy  
- Splints  - Joint-assistive aids
- Education  
- Weight loss  
- Surgery to remove tophi  

 

* CIS does not provide medical advice, diagnosis or treatment. The content is for information purposes only. 

                                                                                                                         Top

Resources

- The Center for Disease Control has more detailed information and facts on gout.

  • Sources: 1. Choi, Hyon K. "The New England Journal of Medicine. Purine-Rich Foods, Dairy and Protein Intake, and the Risk of Gout in Men - NEJM. New England Journal of Medicine, 11 Mar. 2004. Web. 21 May 2013. 
  • 2. Center for Disease Control

                                                                                                                         Top

 * CIS does not provide medical advice, diagnosis or treatment. The content is for informational purposes only.