Arthritis

What is Arthritis?

Arthritis is a group of conditions characterized by inflammation of the joints, causing pain, stiffness, and swelling. It can result from wear and tear, autoimmune responses, or infections and affects people of all ages. Common types include osteoarthritis, rheumatoid arthritis, and psoriatic arthritis.

Symptoms of Arthritis May Include:

• Joint pain and stiffness
• Swelling and tenderness around joints
• Reduced range of motion
• Warmth or redness around affected joints

Facts About Arthritis

Over 58 million adults in the U.S. live with arthritis, making it one of the leading causes of disability. Globally, it affects approximately 350 million people. As populations age, the prevalence of arthritis is expected to rise.

Who is at Risk for Arthritis?

Risk factors for arthritis may include:

• Genetics: Family history increases susceptibility to certain types, such as rheumatoid arthritis.
• Sex: Women are more likely to develop autoimmune-related arthritis, while men are more prone to gout.
• Age: The risk increases with age, particularly for osteoarthritis.
• Race or Ethnicity: Certain types, such as lupus-related arthritis, are more common in specific populations.
• Environment: Exposure to joint injuries, infections, or repetitive physical activities can increase risk.
• Other Risk Factors: Obesity, smoking, and metabolic conditions like diabetes can exacerbate arthritis.

Diagnosis & Management

Arthritis is typically diagnosed through a combination of patient history, physical examination, and imaging tests like X-rays or MRIs. Blood tests may also be used to identify autoimmune forms of arthritis. Early diagnosis is key to managing symptoms and preventing joint damage.

Treatment Options for Arthritis

Medical and Pharmaceutical Treatments

• Medications: Nonsteroidal anti-inflammatory drugs (NSAIDs), corticosteroids, and disease-modifying antirheumatic drugs (DMARDs) are commonly used.
• Injections: Corticosteroid or hyaluronic acid injections may provide relief for certain types.
• Surgical Options: In severe cases, joint replacement surgery may be necessary.

Lifestyle Interventions

• Exercise: Low-impact activities like swimming and walking can improve joint mobility and reduce stiffness.
• Weight Management: Maintaining a healthy weight reduces stress on the joints.
• Physical Therapy: Targeted exercises can strengthen muscles around joints and improve range of motion.

Have You Been Diagnosed With Arthritis?

At Clinical Investigation Specialists, Inc. (CIS Research), we are dedicated to advancing medical care through innovative clinical research. You may be an eligible candidate for a clinical trial researching new treatment options for arthritis. For more information on currently enrolling clinical trials, click here.

Resources

• Arthritis Foundation
• National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
• Find A Study
• Learn More About Clinical Research